Marianthi Kontonika published latest article in Journal of electrocardiology entitled Intra-myocardial growth hormone administration ameliorates arrhythmogenesis during ischemia-reperfusion in rats. This article is available in PubMed with an unique identification number PMID: 27839834 and it is published in . The coauthors of this article are Kontonika M, Barka E, Roumpi M, Vilaeti AD, Baltogiannis GG, Vlahos AP, Agathopoulos S, Kolettis TM.
Cardiology, Cardiovascular Medicine.
Co-Author(s): Kontonika M, Barka E, Roumpi M, Vilaeti AD, Baltogiannis GG, Vlahos AP, Agathopoulos S, Kolettis TM
Affiliation(s): Department of Cardiology, Medical School, University of Ioannina, Greece; Cardiovascular Research Institute, Ioannina, Greece.
PMID 27839834, Year 0
Abstract: Growth hormone, currently under evaluation for the prevention of left ventricular remodeling post-myocardial infarction, displays antiarrhythmic properties in the acute setting. However, it is uncertain whether these actions are retained after ischemia/reperfusion. Using implanted telemetry transmitters, we examined the effects of prolonged, intra-myocardial growth hormone administration in conscious rats. During a 24-h observation period, ventricular tachyarrhythmias and sympathetic activation were attenuated in treated rats, whereas infarct-size was unchanged. These findings call for further study on the antiarrhythmic effects of growth hormone and on the underlying mechanisms.
Journal: Journal of electrocardiology
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